The verse you are referring to is found in Luke 12:48, but it should really be read in the context of verses 42-48:

"And the Lord said, Who then is that faithful and wise steward, whom his lord shall make ruler over his household, to give them their portion of meat in due season?  Blessed is that servant, whom his lord when he cometh shall find so doing.  Of a truth I say unto you, that he will make him ruler over all that he hath.  But and if that servant say in his heart, My lord delayeth his coming; and shall begin to beat the menservants and maidens, and to eat and drink, and to be drunken;  The lord of that servant will come in a day when he looketh not for him, and at an hour when he is not aware, and will cut him in sunder, and will appoint him his portion with the unbelievers.  And that servant, which knew his lord’s will, and prepared not himself, neither did according to his will, shall be beaten with many stripes.  But he that knew not, and did commit things worthy of stripes, shall be beaten with few stripes.  For unto whomsoever much is given, of him shall be much required: and to whom men have committed much, of him they will ask the more."
 
The main idea here is that we are accountable for the knowledge, resources, abilities, etc. that God has blessed us with.  If we have been given much, then He expects that much more from us.  The good news is that all of these blessings come from the Lord and He realizes that humans are not perfect and that we can't do anything right without His help (John 15:5), but we can do all things through Jesus Christ as He strengthens us (Philippians 4:13).  So let's ask the Lord to give us His wisdom and Spirit so that we can be faithful stewards over what He has entrusted to us.  "And now, little children, abide in him; that, when he shall appear, we may have confidence, and not be ashamed before him at his coming."
(1 John 2:28)